Santiago Ponzinibbio has nine losses against nine opponents on his MMA record. For a list of Ponzinibbio's best fights, refer to "Best fights of Santiago Ponzinibbio".
On May 3, 2025 Santiago Ponzinibbio faced off against Daniel Rodriguez in a welterweight bout at age 38. He was coming in with a record of 30-9 (23), and Rodriguez was 38 years old and with a record of 18-5 (12). Ponzinibbio lost the fight via 3rd-round TKO.
On July 13, 2024 Santiago Ponzinibbio faced off against Muslim Salikhov in a welterweight bout at age 37. He was coming in with a record of 29-8 (22), and Salikhov was 40 years old and with a record of 19-5 (15). Ponzinibbio lost the fight via 3-round split decision.
On April 8, 2023 Santiago Ponzinibbio faced off against Kevin Holland in a welterweight bout at age 36. He was coming in with a record of 29-7 (22), and Holland was 30 years old and with a record of 23-9 (19). Ponzinibbio lost the fight via 3rd-round KO.
On May 21, 2022 Santiago Ponzinibbio faced off against Michel Pereira in a welterweight bout at age 35. He was coming in with a record of 28-6 (21), and Pereira was 28 years old and with a record of 27-11 (16). Ponzinibbio lost the fight via 3-round split decision.
On December 11, 2021 Santiago Ponzinibbio faced off against Geoff Neal in a welterweight bout at age 35. He was coming in with a record of 28-5 (21), and Neal was 31 years old and with a record of 13-4 (10). Ponzinibbio lost the fight via 3-round split decision.
On January 16, 2021 Santiago Ponzinibbio faced off against Li Jingliang in a welterweight bout at age 34. He was coming in with a record of 27-4 (21), and Jingliang was 32 years old and with a record of 17-6 (11). Ponzinibbio lost the fight via 1st-round KO.
On June 27, 2015 Santiago Ponzinibbio faced off against Lorenz Larkin in a welterweight bout at age 28. He was coming in with a record of 20-3 (17), and Larkin was 28 years old and with a record of 15-4 (9). Ponzinibbio lost the fight via 2nd-round TKO.
On November 9, 2013 Santiago Ponzinibbio faced off against Ryan LaFlare in a welterweight bout at age 27. He was coming in with a record of 18-2 (16), and LaFlare was 30 years old and with a record of 8-0 (7). Ponzinibbio lost the fight via 3-round unanimous decision.
On July 9, 2011 Santiago Ponzinibbio faced off against Leonardo Mafra in a welterweight bout at age 24. He was coming in with a record of 11-1 (9). Ponzinibbio lost the fight via 1st-round TKO.
