Mike Guymon has six losses against six opponents on his MMA record. For a list of Guymon's best fights, refer to "Best fights of Mike Guymon".
On January 17, 2013 Mike Guymon faced off against Savant Young in a lightweight bout at age 38. He was coming in with a record of 14-6-1 (12), and Young was 36 years old and with a record of 10-9 (6). Guymon lost the fight via 2nd-round KO.
On January 22, 2011 Mike Guymon faced off against DaMarques Johnson in a welterweight bout at age 36. He was coming in with a record of 12-5-1 (11), and Johnson was 28 years old and with a record of 14-8 (12). Guymon lost the fight via 1st-round submission.
On October 23, 2010 Mike Guymon faced off against Daniel Roberts in a welterweight bout at age 36. He was coming in with a record of 12-4-1 (11), and Roberts was 30 years old and with a record of 10-1 (7). Guymon lost the fight via 1st-round submission.
On January 11, 2010 Mike Guymon faced off against Rory MacDonald in a welterweight bout at age 35. He was coming in with a record of 11-3-1 (11), and MacDonald was 20 years old and with a record of 9-0 (9). Guymon lost the fight via 1st-round submission.
On June 16, 2007 Mike Guymon faced off against Pat Healy at age 32. He was coming in with a record of 6-2-1 (6), and Healy was 23 years old and with a record of 17-13 (16). Guymon lost the fight via 3-round split decision.
On May 16, 2003 Mike Guymon faced off against Diego Sanchez at age 28. He was coming in with a record of 2-1-1 (2), and Sanchez was 21 years old and with a record of 4-0 (4). Guymon lost the fight via 1st-round submission.