Matt Serra has seven losses against seven opponents on his MMA record. For a list of Serra's best fights, refer to "Best fights of Matt Serra".
On September 25, 2010 Matt Serra faced off against Chris Lytle in a welterweight bout at age 36. He was coming in with a record of 13-7 (8), and Lytle was 36 years old and with a record of 29-17-5 (23). Serra lost the fight via 3-round unanimous decision.
On May 23, 2009 Matt Serra faced off against Matt Hughes in a welterweight bout at age 34. He was coming in with a record of 12-6 (7), and Hughes was 35 years old and with a record of 42-7 (33). Serra lost the fight via 3-round unanimous decision.
On April 19, 2008 Matt Serra met Georges St-Pierre in a welterweight (UFC Championship) title defense fight. Serra was 33 years old and with a record of 12-5 (7), and St-Pierre was 26 years old and with a record of 15-2 (11). Serra lost the fight via 2nd-round TKO and lost the title.
On June 4, 2005 Matt Serra faced off against Karo Parisyan in a welterweight bout at age 31. He was coming in with a record of 8-4 (5), and Parisyan was 22 years old and with a record of 13-3 (8). Serra lost the fight via 3-round unanimous decision.
On February 28, 2003 Matt Serra faced off against Din Thomas in a lightweight bout at age 28. He was coming in with a record of 6-3 (5), and Thomas was 26 years old and with a record of 15-3 (13). Serra lost the fight via 3-round split decision.
On September 27, 2002 Matt Serra faced off against B.J. Penn in a lightweight bout at age 28. He was coming in with a record of 6-2 (5), and Penn was 23 years old and with a record of 4-1 (4). Serra lost the fight via 3-round unanimous decision.
On May 4, 2001 Matt Serra faced off against Shonie Carter at age 26. He was coming in with a record of 4-1 (4), and Carter was 29 years old and with a record of 18-5-5 (8). Serra lost the fight via 3rd-round KO.