Matt Hughes has nine losses against six opponents on his MMA record. For a list of Hughes's best fights, refer to "Best fights of Matt Hughes".
On September 24, 2011 Matt Hughes faced off against Josh Koscheck in a welterweight bout at age 37. He was coming in with a record of 45-9 (34), and Koscheck was 33 years old and with a record of 15-5 (9). Hughes lost the fight via 1st-round KO.
On November 20, 2010 Matt Hughes faced off against B.J. Penn in a welterweight bout at age 37. He was coming in with a record of 45-8 (34), and Penn was 31 years old and with a record of 15-7-1 (12). Hughes lost the fight via 1st-round KO.
On June 7, 2008 Matt Hughes faced off against Thiago Alves in a welterweight bout at age 34. He was coming in with a record of 42-7 (33), and Alves was 24 years old and with a record of 15-5 (11). Hughes lost the fight via 2nd-round TKO.
On December 29, 2007 Matt Hughes fought Georges St-Pierre in a welterweight title fight for St-Pierre's UFC Championship title. Hughes was 34 years old and with a record of 42-6 (33), and St-Pierre was 26 years old and with a record of 14-2 (10). Hughes lost the fight via 2nd-round submission.
On November 18, 2006 Matt Hughes met Georges St-Pierre in a welterweight (UFC Championship) title defense fight. Hughes was 33 years old and with a record of 41-5 (33), and St-Pierre was 25 years old and with a record of 12-1 (9). Hughes lost the fight via 2nd-round TKO and lost the title.
On January 31, 2004 Matt Hughes met B.J. Penn in a welterweight (UFC Championship) title defense fight. Hughes was 30 years old and with a record of 35-4 (28), and Penn was 25 years old and with a record of 6-1-1 (5). Hughes lost the fight via 1st-round submission and lost the title.
On February 8, 2001 Matt Hughes faced off against José Landi-Jons in a middleweight bout at age 27. He was coming in with a record of 22-3 (17). Hughes lost the fight via 1st-round KO.
On December 16, 2000 Matt Hughes faced off against Dennis Hallman at age 27. He was coming in with a record of 22-2 (17), and Hallman was 25 years old and with a record of 17-4 (12). Hughes lost the fight via 1st-round submission.
On October 17, 1998 Matt Hughes faced off against Dennis Hallman at age 25. He was coming in with a record of 4-1 (3), and Hallman was 22 years old and with a record of 10-0 (8). Hughes lost the fight via 1st-round choke-out.