Marcelo Guimarães has two losses against two opponents on his MMA record. For a list of Guimarães's best fights, refer to "Best fights of Marcelo Guimarães".
On March 5, 2016 Marcelo Guimarães faced off against Vitor Miranda in a middleweight bout at age 32. He was coming in with a record of 9-2-1 (2), and Miranda was 36 years old and with a record of 11-4 (10). Guimarães lost the fight via 2nd-round TKO.
On March 3, 2013 Marcelo Guimarães faced off against Hyun Gyu Lim in a welterweight bout at age 29. He was coming in with a record of 8-1-1 (2). Guimarães lost the fight via 2nd-round KO.