Junior dos Santos has 10 losses against nine opponents on his MMA record. For a list of Santos's best fights, refer to "Best fights of Junior dos Santos".
On May 20, 2022 Junior dos Santos faced off against Yorgan De Castro in a heavyweight bout at age 38. He was coming in with a record of 21-10 (16), and De Castro was 34 years old and with a record of 8-3 (6). Santos lost the fight via 3rd-round TKO.
On December 12, 2020 Junior dos Santos faced off against Ciryl Gane in a heavyweight bout at age 36. He was coming in with a record of 21-9 (16), and Gane was 30 years old and with a record of 6-0 (5). Santos lost the fight via 2nd-round TKO.
On August 15, 2020 Junior dos Santos faced off against Jairzinho Rozenstruik in a heavyweight bout at age 36. He was coming in with a record of 21-8 (16), and Rozenstruik was 32 years old and with a record of 10-1 (9). Santos lost the fight via 2nd-round TKO.
On January 25, 2020 Junior dos Santos faced off against Curtis Blaydes in a heavyweight bout at age 35. He was coming in with a record of 21-7 (16), and Blaydes was 28 years old and with a record of 12-2 (9). Santos lost the fight via 2nd-round TKO.
On June 29, 2019 Junior dos Santos faced off against Francis Ngannou in a heavyweight bout at age 35. He was coming in with a record of 21-6 (16), and Ngannou was 32 years old and with a record of 13-3 (13). Santos lost the fight via 1st-round TKO.
On May 13, 2017 Junior dos Santos fought Stipe Miocic in a heavyweight title fight for Miocic's UFC Championship title. Santos was 33 years old and with a record of 18-5 (14), and Miocic was 34 years old and with a record of 16-2 (13). Santos lost the fight via 1st-round TKO.
On December 19, 2015 Junior dos Santos faced off against Alistair Overeem in a heavyweight bout at age 31. He was coming in with a record of 17-4 (14), and Overeem was 35 years old and with a record of 39-14 (35). Santos lost the fight via 2nd-round TKO.
On October 19, 2013 Junior dos Santos fought Cain Velasquez in a heavyweight title fight for Velasquez' UFC Championship title. Santos was 29 years old and with a record of 16-3 (14), and Velasquez was 31 years old and with a record of 12-1 (10). Santos lost the fight via 5th-round TKO.
On December 29, 2012 Junior dos Santos met Cain Velasquez in a heavyweight (UFC Championship) title defense fight. Santos was 28 years old and with a record of 15-2 (13), and Velasquez was 30 years old and with a record of 10-1 (9). Santos lost the fight via 5-round unanimous decision and lost the title.
On November 10, 2007 Junior dos Santos faced off against Joaquim Ferreira in a light-heavyweight bout at age 23. He was coming in with a record of 5-1 (5). Santos lost the fight via 1st-round submission.
