Here is a list of Santos's best fights. For a list of Santos's losses, refer to "Junior dos Santos Losses".
On November 12, 2011 Junior dos Santos fought Cain Velasquez in a heavyweight title fight for Velasquez' UFC Championship title. Santos was 27 years old and with a record of 14-1 (12), and Velasquez was 29 years old and with a record of 9-0 (8). Santos stopped Cain Velasquez via 1st-round KO and is crowned the new UFC heavyweight champion.
On May 26, 2012 Junior dos Santos met Frank Mir in a heavyweight (UFC Championship) title defense fight. Santos was 28 years old and with a record of 15-1 (13), and Mir was 33 years old and with a record of 16-5 (9). Santos stopped Frank Mir via 2nd-round TKO and successfully defended his title.
On February 21, 2009 Junior dos Santos faced off against Stefan Struve in a heavyweight bout at age 25. He was coming in with a record of 8-1 (8), and Struve was 21 years old and with a record of 16-2 (15). Santos stopped Stefan Struve via TKO.
On March 21, 2010 Junior dos Santos faced off against Gabriel Gonzaga in a heavyweight bout at age 26. He was coming in with a record of 11-1 (11), and Gonzaga was 30 years old and with a record of 11-4 (11). Santos stopped Gabriel Gonzaga via TKO.
On March 9, 2019 Junior dos Santos faced off against Derrick Lewis in a heavyweight bout at age 35. He was coming in with a record of 21-5 (16), and Lewis was 34 years old and with a record of 21-6 (19). Santos stopped Derrick Lewis via TKO.
On October 25, 2008 Junior dos Santos faced off against Fabrício Werdum in a heavyweight bout at age 24. He was coming in with a record of 7-1 (7), and Werdum was 31 years old and with a record of 11-3-1 (10). Santos stopped Fabrício Werdum via TKO.
On September 19, 2009 Junior dos Santos faced off against Mirko Cro Cop in a heavyweight bout at age 25. He was coming in with a record of 9-1 (9), and Cop was 35 years old and with a record of 25-6-2 (22). Santos stopped Mirko Cro Cop via TKO.
On December 2, 2018 Junior dos Santos faced off against Tai Tuivasa in a heavyweight bout at age 34. He was coming in with a record of 20-5 (15), and Tuivasa was 25 years old and with a record of 9-0 (8). Santos stopped Tai Tuivasa via TKO.
On January 2, 2010 Junior dos Santos faced off against Gilbert Yvel in a heavyweight bout at age 25. He was coming in with a record of 10-1 (10), and Yvel was 33 years old and with a record of 36-13-1 (36). Santos stopped Gilbert Yvel via TKO.
On June 11, 2011 Junior dos Santos faced off against Shane Carwin in a heavyweight bout at age 27. He was coming in with a record of 13-1 (11), and Carwin was 36 years old and with a record of 12-1 (12). Santos won the fight via 3-round unanimous decision.