Jorge Santiago has 12 losses against 12 opponents on his MMA record. For a list of Santiago's best fights, refer to "Best fights of Jorge Santiago".
On August 10, 2013 Jorge Santiago faced off against Gerald Harris in a middleweight bout at age 32. He was coming in with a record of 25-12 (22), and Harris was 33 years old and with a record of 21-5 (15). Santiago lost the fight via 3-round unanimous decision.
On February 16, 2013 Jorge Santiago faced off against Gunnar Nelson in a middleweight bout at age 32. He was coming in with a record of 25-11 (22), and Nelson was 24 years old and with a record of 10-0-1 (10). Santiago lost the fight via 3-round unanimous decision.
On October 8, 2011 Jorge Santiago faced off against Demian Maia in a middleweight bout at age 30. He was coming in with a record of 23-10 (20), and Maia was 33 years old and with a record of 14-3 (9). Santiago lost the fight via 3-round unanimous decision.
On May 28, 2011 Jorge Santiago faced off against Brian Stann in a middleweight bout at age 30. He was coming in with a record of 23-9 (20), and Stann was 30 years old and with a record of 10-3 (8). Santiago lost the fight via 2nd-round KO.
On November 7, 2009 Jorge Santiago faced off against Mamed Khalidov in a middleweight bout at age 29. He was coming in with a record of 21-8 (19), and Khalidov was 29 years old and with a record of 19-3-1 (18). Santiago lost the fight via 1st-round KO.
On December 13, 2006 Jorge Santiago faced off against Alan Belcher in a middleweight bout at age 26. He was coming in with a record of 12-7 (11), and Belcher was 22 years old and with a record of 9-3 (8). Santiago lost the fight via 3rd-round KO.
On August 17, 2006 Jorge Santiago faced off against Chris Leben in a middleweight bout at age 25. He was coming in with a record of 12-6 (11), and Leben was 26 years old and with a record of 15-3 (11). Santiago lost the fight via 2nd-round KO.
On August 5, 2005 Jorge Santiago fought Joey Villaseñor in a middleweight title fight for Villaseñor's KOTC Championship title. Santiago was 24 years old and with a record of 8-5 (7), and Villaseñor was 29 years old and with a record of 18-3 (18). Santiago lost the fight via 3-round unanimous decision.
On June 12, 2005 Jorge Santiago faced off against Jordan Radev in a middleweight bout at age 24. He was coming in with a record of 8-4 (7), and Radev was 29 years old and with a record of 5-0 (5). Santiago lost the fight via 2-round unanimous decision.
On June 12, 2004 Jorge Santiago fought Diego Sanchez in a welterweight title fight for the KOTC Championship title. Santiago was 23 years old and with a record of 7-3 (6), and Sanchez was 22 years old and with a record of 10-0 (10). Santiago lost the fight via 3-round unanimous decision.
On December 6, 2003 Jorge Santiago faced off against Keith Wisniewski at age 23. He was coming in with a record of 5-2 (4), and Wisniewski was 22 years old and with a record of 14-5-1 (12). Santiago lost the fight via 3rd-round KO.
On August 10, 2003 Jorge Santiago faced off against Manny Gamburyan at age 22. He was coming in with a record of 3-1 (3), and Gamburyan was 22 years old and with a record of 4-1 (3). Santiago lost the fight via 1st-round KO.
