Here is a list of Pyfer's best fights. For a list of Pyfer's losses, refer to "Joe Pyfer Losses".
On April 8, 2023 Joe Pyfer faced off against Gerald Meerschaert in a middleweight bout at age 26. He was coming in with a record of 11-2 (9), and Meerschaert was 35 years old and with a record of 35-15 (30). Pyfer stopped Gerald Meerschaert via TKO.
On September 17, 2022 Joe Pyfer faced off against Alen Amedovski in a middleweight bout at age 26. He was coming in with a record of 10-2 (8), and Amedovski was 34 years old and with a record of 8-3 (8). Pyfer stopped Alen Amedovski via TKO.
On October 7, 2023 Joe Pyfer faced off against Abdul Razak Alhassan in a middleweight bout at age 27. He was coming in with a record of 12-2 (9), and Alhassan was 38 years old and with a record of 12-5 (12). Pyfer stopped Abdul Razak Alhassan via choke-out.
On June 29, 2024 Joe Pyfer faced off against Marc-André Barriault in a middleweight bout at age 27. He was coming in with a record of 13-3 (10), and Barriault was 34 years old and with a record of 16-7 (11). Pyfer stopped Marc-André Barriault via KO.
On June 7, 2025 Joe Pyfer faced off against Kelvin Gastelum in a middleweight bout at age 28. He was coming in with a record of 14-3 (10), and Gastelum was 33 years old and with a record of 19-9 (11). Pyfer won the fight via 3-round unanimous decision.
On December 17, 2021 Joe Pyfer faced off against Austin Trotman in a middleweight bout at age 25. He was coming in with a record of 8-2 (6). Pyfer stopped Austin Trotman via KO.