Dustin Poirier has 10 losses against 10 opponents on his MMA record. For a list of Poirier's best fights, refer to "Best fights of Dustin Poirier".
On July 19, 2025 Dustin Poirier faced off against Max Holloway in a lightweight bout at age 36. He was coming in with a record of 30-10 (23), and Holloway was 33 years old and with a record of 26-8 (14). Poirier lost the fight via 5-round unanimous decision.
On June 1, 2024 Dustin Poirier fought Islam Makhachev in a lightweight title fight for Makhachev's UFC Championship title. Poirier was 35 years old and with a record of 30-9 (23), and Makhachev was 32 years old and with a record of 25-1 (16). Poirier lost the fight via 5th-round submission.
On July 29, 2023 Dustin Poirier faced off against Justin Gaethje in a lightweight bout at age 34. He was coming in with a record of 29-8 (22), and Gaethje was 34 years old and with a record of 24-4 (20). Poirier lost the fight via 2nd-round KO.
On December 11, 2021 Dustin Poirier fought Charles Oliveira in a lightweight title fight for Oliveira's UFC Championship title. Poirier was 32 years old and with a record of 28-7 (21), and Oliveira was 32 years old and with a record of 31-8 (28). Poirier lost the fight via 3rd-round submission.
On September 7, 2019 Dustin Poirier fought Khabib Nurmagomedov in a lightweight title fight for Nurmagomedov's UFC Championship title. Poirier was 30 years old and with a record of 25-6 (19), and Nurmagomedov was 30 years old and with a record of 27-0 (17). Poirier lost the fight via 3rd-round submission.
On September 17, 2016 Dustin Poirier faced off against Michael Johnson in a lightweight bout at age 27. He was coming in with a record of 20-5 (16), and Johnson was 30 years old and with a record of 16-10 (9). Poirier lost the fight via 1st-round KO.
On September 27, 2014 Dustin Poirier faced off against Conor McGregor in a featherweight bout at age 25. He was coming in with a record of 16-4 (13), and McGregor was 26 years old and with a record of 15-2 (14). Poirier lost the fight via 1st-round TKO.
On February 16, 2013 Dustin Poirier faced off against Cub Swanson in a featherweight bout at age 24. He was coming in with a record of 13-3 (11), and Swanson was 29 years old and with a record of 18-5 (14). Poirier lost the fight via 3-round unanimous decision.
On May 15, 2012 Dustin Poirier faced off against Jung Chan-sung in a featherweight bout at age 23. He was coming in with a record of 12-2 (10), and Chan-sung was 25 years old and with a record of 12-3 (10). Poirier lost the fight via 4th-round choke-out.
On August 18, 2010 Dustin Poirier faced off against Danny Castillo at age 21. He was coming in with a record of 7-1 (7), and Castillo was 30 years old and with a record of 8-3 (7). Poirier lost the fight via 3-round unanimous decision.