Ismael Laguna has nine losses against seven opponents on his boxing record. For a list of Laguna's best fights, refer to "Best fights of Ismael Laguna".
On September 13, 1971 Ismael Laguna fought Ken Buchanan in a lightweight world-title fight for Buchanan's WBA and The Ring titles. Laguna was 28 years old and with a record of 65-9-1 (37), and Buchanan was 26 years old and with a record of 40-1 (14). Laguna lost the fight via 15-round unanimous decision.
On June 22, 1971 Ismael Laguna faced off against Eddie Linder at age 27. He was coming in with a record of 65-8-1 (37). Laguna lost the fight via 10-round split decision.
On September 26, 1970 Ismael Laguna met Ken Buchanan in a lightweight () world-title defense fight. Laguna was 27 years old and with a record of 63-7-1 (37), and Buchanan was 25 years old and with a record of 36-1 (13). Laguna lost the fight via 15-round split decision and lost the titles.
On May 24, 1969 Ismael Laguna faced off against Eugenio Espinoza at age 25. He was coming in with a record of 58-6-1 (34). Laguna lost the fight via 10-round unanimous decision.
On August 16, 1967 Ismael Laguna fought Carlos Ortiz in a lightweight world-title fight for Ortiz' WBA, WBC and The Ring titles. Laguna was 24 years old and with a record of 47-5-1 (30), and Ortiz was 30 years old and with a record of 50-5-1 (22). Laguna lost the fight via 15-round unanimous decision.
On March 19, 1966 Ismael Laguna faced off against Gabriel Elorde at age 22. He was coming in with a record of 41-4-1 (27), and Elorde was 30 years old and with a record of 78-19-2 (29). Laguna lost the fight via 10-round unanimous decision.
On November 13, 1965 Ismael Laguna met Carlos Ortiz in a lightweight (WBA, WBC, The Ring) world-title defense fight. Laguna was 22 years old and with a record of 40-3-1 (26), and Ortiz was 29 years old and with a record of 45-5 (18). Laguna lost the fight via 15-round unanimous decision and lost the titles.
On June 1, 1964 Ismael Laguna faced off against Vicente Saldivar at age 20. He was coming in with a record of 34-2 (23), and Saldivar was 21 years old and with a record of 24-1 (20). Laguna lost the fight via 10-round unanimous decision.
On June 7, 1963 Ismael Laguna faced off against Antonio Herrera at age 19. He was coming in with a record of 27-1 (19). Laguna lost the fight via 10-round points decision.
