Here is a list of Prograis's best fights. For a list of Prograis's losses, refer to "Regis Prograis Losses".
On October 27, 2018 Regis Prograis faced off against Terry Flanagan in a super-lightweight bout at age 29. He was coming in with a record of 23-0 (19), and Flanagan was 29 years old and with a record of 33-1 (13). Prograis won the fight via 12-round unanimous decision.
On November 26, 2022 Regis Prograis fought Jose Zepeda in a super-lightweight world-title fight for the WBC title. Prograis was 33 years old and with a record of 28-1 (24), and Zepeda was 33 years old and with a record of 36-2 (28). Prograis stopped Jose Zepeda via 11th-round KO and is crowned the new super-lightweight world champion.
On March 9, 2018 Regis Prograis fought Julius Indongo in a super-lightweight world-title fight for the WBC title. Prograis was 29 years old and with a record of 21-0 (18), and Indongo was 35 years old and with a record of 22-1 (11). Prograis stopped Julius Indongo via 2nd-round TKO and is crowned the new super-lightweight world champion.
On April 27, 2019 Regis Prograis fought Kiryl Relikh in a super-lightweight world-title fight for Relikh's WBA title. Prograis was 30 years old and with a record of 24-0 (20), and Relikh was 29 years old and with a record of 23-2 (19). Prograis stopped Kiryl Relikh via 6th-round TKO and is crowned the new super-lightweight world champion.
On July 14, 2018 Regis Prograis faced off against Juan Jose Velasco in a super-lightweight bout at age 29. He was coming in with a record of 22-0 (19), and Velasco was 31 years old and with a record of 20-0 (12). Prograis stopped Juan Jose Velasco via TKO.
On June 17, 2023 Regis Prograis met Danielito Zorrilla in a super-lightweight (WBC) world-title defense fight. Prograis was 34 years old and with a record of 29-1 (24), and Zorrilla was 29 years old and with a record of 17-1 (13). Prograis won the fight via 12-round split decision and successfully defended his title.
On March 19, 2022 Regis Prograis faced off against Tyrone McKenna in a super-lightweight bout at age 33. He was coming in with a record of 27-1 (23), and McKenna was 32 years old and with a record of 22-2-1 (6). Prograis stopped Tyrone McKenna via TKO.
On December 11, 2015 Regis Prograis faced off against Abel Ramos in a super-lightweight bout at age 26. He was coming in with a record of 16-0 (13), and Ramos was 24 years old and with a record of 14-0-2 (9). Prograis stopped Abel Ramos via retirement.
On August 2, 2025 Regis Prograis faced off against Joseph Diaz in a super-lightweight bout at age 36. He was coming in with a record of 30-3 (24), and Diaz was 32 years old and with a record of 33-7-1 (15). Prograis won the fight via 10-round unanimous decision.
On March 25, 2016 Regis Prograis faced off against Aaron Herrera in a super-lightweight bout at age 27. He was coming in with a record of 17-0 (14), and Herrera was 25 years old and with a record of 29-4-1 (18). Prograis stopped Aaron Herrera via KO.