Alexandro Santiago has five losses against five opponents on his boxing record. For a list of Santiago's best fights, refer to "Best fights of Alexandro Santiago".
On November 30, 2024 Alexandro Santiago faced off against Jose Calderon Cervantes in a bantamweight bout at age 28. He was coming in with a record of 28-5-5 (14). Santiago lost the fight via 10-round majority decision.
On February 24, 2024 Alexandro Santiago met Junto Nakatani in a bantamweight (WBC) world-title defense fight. Santiago was 28 years old and with a record of 28-4-5 (14), and Nakatani was 26 years old and with a record of 26-0 (19). Santiago lost the fight via 6th-round TKO and lost the title.
On November 27, 2021 Alexandro Santiago faced off against Gary Antonio Russell in a bantamweight bout at age 25. He was coming in with a record of 24-3-5 (13), and Russell was 28 years old and with a record of 18-0 (12). Santiago lost the fight via 10-round majority decision.
On November 15, 2014 Alexandro Santiago faced off against Johnny Michel Garcia at age 18. He was coming in with a record of 8-2-1 (3). Santiago lost the fight via 6-round split decision.
On December 21, 2013 Alexandro Santiago faced off against Hector Flores at age 17. He was coming in with a record of 7-1-1 (3). Santiago lost the fight via 6-round unanimous decision.