Yōsuke Nishijima has five losses against five opponents on his MMA record. For a list of Nishijima's best fights, refer to "Best fights of Yōsuke Nishijima".
On December 31, 2007 Yōsuke Nishijima faced off against Melvin Manhoef in a middleweight bout at age 34. He was coming in with a record of 0-5 (0), and Manhoef was 31 years old and with a record of 19-4-1 (18). Nishijima lost the fight via 1st-round TKO.
On October 21, 2006 Yōsuke Nishijima faced off against Phil Baroni in a middleweight bout at age 33. He was coming in with a record of 0-4 (0), and Baroni was 30 years old and with a record of 9-7 (8). Nishijima lost the fight via 1st-round choke-out.
On September 10, 2006 Yōsuke Nishijima faced off against Evangelista Santos in a middleweight bout at age 33. He was coming in with a record of 0-3 (0), and Santos was 28 years old and with a record of 14-9 (12). Nishijima lost the fight via 1st-round submission.
On May 5, 2006 Yōsuke Nishijima faced off against Hidehiko Yoshida at age 32. He was coming in with a record of 0-2 (0), and Yoshida was 36 years old and with a record of 6-3-1 (5). Nishijima lost the fight via 1st-round submission.
On February 26, 2006 Yōsuke Nishijima faced off against Mark Hunt at age 32. He was coming in with a record of 0-1 (0), and Hunt was 31 years old and with a record of 3-1 (1). Nishijima lost the fight via 3rd-round KO.