Here is a list of De Castro's best fights. For a list of De Castro's losses, refer to "Yorgan De Castro Losses".
On October 6, 2019 Yorgan De Castro faced off against Justin Tafa in a heavyweight bout at age 31. He was coming in with a record of 6-0 (5), and Tafa was 25 years old and with a record of 3-0 (3). De Castro stopped Justin Tafa via KO.
On May 20, 2022 Yorgan De Castro faced off against Junior dos Santos in a heavyweight bout at age 34. He was coming in with a record of 9-3 (7), and Santos was 38 years old and with a record of 21-9 (16). De Castro stopped Junior dos Santos via TKO.