Thanh Le has four losses against three opponents on his MMA record. For a list of Le's best fights, refer to "Best fights of Thanh Le".
On March 1, 2024 Thanh Le fought Tang Kai in a featherweight title fight for Kai's ONE Championship title. Le was 38 years old and with a record of 14-4 (14), and Kai was 28 years old and with a record of 18-2 (14). Le lost the fight via 3rd-round TKO.
On August 26, 2022 Thanh Le met Tang Kai in a featherweight (ONE Championship) title defense fight. Le was 36 years old and with a record of 13-3 (13), and Kai was 26 years old and with a record of 17-2 (14). Le lost the fight via 5-round unanimous decision and lost the title.
On May 25, 2018 Thanh Le fought Kevin Aguilar in a featherweight title fight for Aguilar's LFA Championship title. Le was 32 years old and with a record of 8-2 (8), and Aguilar was 29 years old and with a record of 13-1 (10). Le lost the fight via 1st-round KO.
On November 8, 2013 Thanh Le faced off against Robert Dunn in a lightweight bout at age 28. He was coming in with a record of 0-1 (0). Le lost the fight via 1st-round submission.