Taila Santos has four losses against four opponents on her MMA record. For a list of Santos's best fights, refer to "Best fights of Taila Santos".
On November 29, 2024 Taila Santos faced off against Dakota Ditcheva in a flyweight bout at age 31. She was coming in with a record of 22-4 (14), and Ditcheva was 26 years old and with a record of 13-0 (12). Santos lost the fight via 2nd-round TKO.
On August 26, 2023 Taila Santos faced off against Erin Blanchfield in a flyweight bout at age 30. She was coming in with a record of 19-3 (13), and Blanchfield was 24 years old and with a record of 11-1 (6). Santos lost the fight via 3-round unanimous decision.
On June 12, 2022 Taila Santos fought Valentina Shevchenko in a flyweight title fight for Shevchenko's UFC Women's Championship title. Santos was 28 years old and with a record of 19-2 (13), and Shevchenko was 34 years old and with a record of 22-3 (15). Santos lost the fight via 5-round split decision.
On February 2, 2019 Taila Santos faced off against Mara Romero Borella in a flyweight bout at age 25. She was coming in with a record of 15-1 (12), and Borella was 32 years old and with a record of 11-5 (7). Santos lost the fight via 3-round split decision.