Shane Carwin has two losses against two opponents on his MMA record. For a list of Carwin's best fights, refer to "Best fights of Shane Carwin".
On June 11, 2011 Shane Carwin faced off against Junior dos Santos in a heavyweight bout at age 36. He was coming in with a record of 12-2 (12), and Santos was 27 years old and with a record of 12-1 (11). Carwin lost the fight via 3-round unanimous decision.
On July 3, 2010 Shane Carwin fought Brock Lesnar in a heavyweight title fight for Lesnar's UFC Championship title. Carwin was 35 years old and with a record of 12-1 (12), and Lesnar was 32 years old and with a record of 4-1 (3). Carwin lost the fight via 2nd-round submission.