Sean Spencer has seven losses against seven opponents on his MMA record. For a list of Spencer's best fights, refer to "Best fights of Sean Spencer".
On August 10, 2018 Sean Spencer faced off against Bilal Williams in a middleweight bout at age 31. He was coming in with a record of 12-7 (4). Spencer lost the fight via 2nd-round TKO.
On September 10, 2016 Sean Spencer faced off against Yancy Medeiros in a middleweight bout at age 29. He was coming in with a record of 12-6 (4), and Medeiros was 29 years old and with a record of 12-4 (9). Spencer lost the fight via 2nd-round submission.
On February 6, 2016 Sean Spencer faced off against Mike Pyle in a middleweight bout at age 28. He was coming in with a record of 12-5 (4). Spencer lost the fight via 3rd-round TKO.
On January 18, 2015 Sean Spencer faced off against Cathal Pendred in a middleweight bout at age 27. He was coming in with a record of 12-4 (4), and Pendred was 27 years old and with a record of 15-2-1 (6). Spencer lost the fight via 3-round unanimous decision.
On March 15, 2014 Sean Spencer faced off against Alex Garcia in a middleweight bout at age 26. He was coming in with a record of 11-3 (4), and Garcia was 26 years old and with a record of 11-1 (10). Spencer lost the fight via 3-round split decision.
On January 26, 2013 Sean Spencer faced off against Rafael Natal in a middleweight bout at age 25. He was coming in with a record of 9-2 (4), and Natal was 30 years old and with a record of 14-4-1 (10). Spencer lost the fight via 3rd-round submission.
On August 13, 2011 Sean Spencer faced off against Ali Hanjani in a welterweight bout at age 24. He was coming in with a record of 6-1 (3). Spencer lost the fight via 1st-round submission.