Scott Holtzman has six losses against six opponents on his MMA record. For a list of Holtzman's best fights, refer to "Best fights of Scott Holtzman".
On December 3, 2022 Scott Holtzman faced off against Clay Guida in a lightweight bout at age 39. He was coming in with a record of 14-6 (7), and Guida was 40 years old and with a record of 37-22 (21). Holtzman lost the fight via 3-round split decision.
On April 10, 2021 Scott Holtzman faced off against Mateusz Gamrot in a lightweight bout at age 37. He was coming in with a record of 14-5 (7), and Gamrot was 30 years old and with a record of 17-1 (9). Holtzman lost the fight via 2nd-round KO.
On August 8, 2020 Scott Holtzman faced off against Beneil Dariush in a lightweight bout at age 36. He was coming in with a record of 14-4 (7), and Dariush was 31 years old and with a record of 18-4-1 (12). Holtzman lost the fight via 1st-round KO.
On February 17, 2019 Scott Holtzman faced off against Nik Lentz in a lightweight bout at age 35. He was coming in with a record of 12-3 (6), and Lentz was 34 years old and with a record of 29-9-2 (19). Holtzman lost the fight via 3-round unanimous decision.
On December 17, 2016 Scott Holtzman faced off against Josh Emmett in a lightweight bout at age 33. He was coming in with a record of 9-2 (5), and Emmett was 31 years old and with a record of 10-0 (5). Holtzman lost the fight via 3-round unanimous decision.
On January 2, 2016 Scott Holtzman faced off against Drew Dober in a lightweight bout at age 32. He was coming in with a record of 8-1 (5), and Dober was 27 years old and with a record of 15-7 (11). Holtzman lost the fight via 3-round unanimous decision.