Here is a list of Sicilia's best fights. For a list of Sicilia's losses, refer to "Sam Sicilia Losses".
On November 9, 2013 Sam Sicilia faced off against Godofredo Pepey in a featherweight bout at age 27. He was coming in with a record of 12-3 (11), and Pepey was 26 years old and with a record of 9-2 (8). Sicilia stopped Godofredo Pepey via TKO.
On January 24, 2015 Sam Sicilia faced off against Akira Corassani in a featherweight bout at age 28. He was coming in with a record of 14-5 (12), and Corassani was 32 years old and with a record of 12-5 (4). Sicilia stopped Akira Corassani via KO.
On December 1, 2017 Sam Sicilia faced off against Marcos Galvão in a featherweight bout at age 31. He was coming in with a record of 16-8 (12), and Galvão was 35 years old and with a record of 18-8-1 (5). Sicilia won the fight via 3-round unanimous decision.
On December 14, 2018 Sam Sicilia faced off against Derek Campos in a featherweight bout at age 32. He was coming in with a record of 17-9 (12), and Campos was 30 years old and with a record of 19-7 (11). Sicilia won the fight via 3-round split decision.
On June 1, 2012 Sam Sicilia faced off against Cristiano Marcello in a lightweight bout at age 26. He was coming in with a record of 11-1 (10), and Marcello was 34 years old and with a record of 12-3 (11). Sicilia stopped Cristiano Marcello via KO.
On May 24, 2014 Sam Sicilia faced off against Aaron Phillips in a featherweight bout at age 28. He was coming in with a record of 13-4 (11). Sicilia won the fight via 3-round unanimous decision.
On July 15, 2015 Sam Sicilia faced off against Yaotzin Meza in a featherweight bout at age 29. He was coming in with a record of 15-5 (12), and Meza was 34 years old and with a record of 21-9 (12). Sicilia won the fight via 3-round unanimous decision.