Sam Hughes has six losses against six opponents on her MMA record. For a list of Hughes's best fights, refer to "Best fights of Sam Hughes".
On February 24, 2024 Sam Hughes faced off against Yazmin Jauregui in a strawweight bout at age 31. She was coming in with a record of 8-6 (4). Hughes lost the fight via 3-round unanimous decision.
On October 15, 2022 Sam Hughes faced off against Piera Rodríguez in a strawweight bout at age 30. She was coming in with a record of 7-5 (4). Hughes lost the fight via 3-round unanimous decision.
On November 20, 2021 Sam Hughes faced off against Luana Pinheiro in a strawweight bout at age 29. She was coming in with a record of 5-4 (3), and Pinheiro was 28 years old and with a record of 9-1 (7). Hughes lost the fight via 3-round unanimous decision.
On May 1, 2021 Sam Hughes faced off against Loma Lookboonmee in a strawweight bout at age 28. She was coming in with a record of 5-3 (3), and Lookboonmee was 25 years old and with a record of 5-2 (1). Hughes lost the fight via 3-round unanimous decision.
On December 12, 2020 Sam Hughes faced off against Tecia Torres in a strawweight bout at age 28. She was coming in with a record of 5-2 (3). Hughes lost the fight via 1st-round TKO.
On July 17, 2020 Sam Hughes faced off against Vanessa Demopoulos in a strawweight bout at age 28. She was coming in with a record of 4-1 (3). Hughes lost the fight via 4th-round choke-out.
