Here is a list of Spann's best fights. For a list of Spann's losses, refer to "Ryan Spann Losses".
On May 11, 2019 Ryan Spann faced off against Antônio Rogério Nogueira in a light-heavyweight bout at age 27. He was coming in with a record of 16-5 (14), and Nogueira was 42 years old and with a record of 23-8 (13). Spann stopped Antônio Rogério Nogueira via KO.
On March 13, 2021 Ryan Spann faced off against Misha Cirkunov in a light-heavyweight bout at age 29. He was coming in with a record of 19-6 (16), and Cirkunov was 34 years old and with a record of 15-5 (13). Spann stopped Misha Cirkunov via TKO.
On November 12, 2022 Ryan Spann faced off against Dominick Reyes in a light-heavyweight bout at age 31. He was coming in with a record of 21-7 (18), and Reyes was 32 years old and with a record of 12-3 (9). Spann stopped Dominick Reyes via KO.
On May 14, 2022 Ryan Spann faced off against Ion Cuțelaba in a light-heavyweight bout at age 30. He was coming in with a record of 20-7 (17), and Cuțelaba was 28 years old and with a record of 16-6-1 (14). Spann stopped Ion Cuțelaba via submission.
On July 19, 2025 Ryan Spann faced off against Łukasz Brzeski in a heavyweight bout at age 33. He was coming in with a record of 23-11 (20). Spann stopped Łukasz Brzeski via submission.
On September 22, 2018 Ryan Spann faced off against Luis Henrique in a light-heavyweight bout at age 27. He was coming in with a record of 15-5 (13), and Henrique was 25 years old and with a record of 10-4 (7). Spann won the fight via 3-round unanimous decision.
On October 5, 2024 Ryan Spann faced off against Ovince Saint Preux in a light-heavyweight bout at age 33. He was coming in with a record of 22-10 (19), and Preux was 41 years old and with a record of 27-17 (18). Spann stopped Ovince Saint Preux via submission.
On October 12, 2019 Ryan Spann faced off against Devin Clark in a light-heavyweight bout at age 28. He was coming in with a record of 17-5 (15), and Clark was 29 years old and with a record of 10-3 (4). Spann stopped Devin Clark via submission.
On May 9, 2020 Ryan Spann faced off against Sam Alvey in a light-heavyweight bout at age 28. He was coming in with a record of 18-5 (15), and Alvey was 34 years old and with a record of 33-13 (22). Spann won the fight via 3-round split decision.
On June 19, 2018 Ryan Spann faced off against Emiliano Sordi in a light-heavyweight bout at age 26. He was coming in with a record of 14-5 (13), and Sordi was 27 years old and with a record of 16-6 (16). Spann stopped Emiliano Sordi via submission.
