Ryan Janes has three losses against three opponents on his MMA record. For a list of Janes's best fights, refer to "Best fights of Ryan Janes".
On July 16, 2017 Ryan Janes faced off against Jack Marshman in a middleweight bout at age 35. He was coming in with a record of 9-3 (7), and Marshman was 27 years old and with a record of 21-6 (18). Janes lost the fight via 3-round unanimous decision.
On February 19, 2017 Ryan Janes faced off against Gerald Meerschaert in a middleweight bout at age 35. He was coming in with a record of 9-2 (7), and Meerschaert was 29 years old and with a record of 26-8 (24). Janes lost the fight via 1st-round submission.
On May 8, 2009 Ryan Janes faced off against Mike Hackert at age 27. He was coming in with a record of 1-1 (1). Janes lost the fight via 3-round unanimous decision.