Megan Anderson has five losses against five opponents on her MMA record. For a list of Anderson's best fights, refer to "Best fights of Megan Anderson".
On March 6, 2021 Megan Anderson fought Amanda Nunes in a featherweight title fight for Nunes' UFC Women's Championship title. Anderson was 31 years old and with a record of 11-5 (9), and Nunes was 32 years old and with a record of 20-4 (15). Anderson lost the fight via 1st-round submission.
On May 18, 2019 Megan Anderson faced off against Felicia Spencer in a featherweight bout at age 29. She was coming in with a record of 9-4 (7), and Spencer was 28 years old and with a record of 6-0 (4). Anderson lost the fight via 1st-round submission.
On June 9, 2018 Megan Anderson faced off against Holly Holm in a featherweight bout at age 28. She was coming in with a record of 8-3 (6), and Holm was 36 years old and with a record of 11-4 (8). Anderson lost the fight via 3-round unanimous decision.
On September 12, 2015 Megan Anderson faced off against Cindy Dandois in a featherweight bout at age 25. She was coming in with a record of 4-2 (2), and Dandois was 30 years old and with a record of 5-2 (3). Anderson lost the fight via 2nd-round submission.
On November 16, 2013 Megan Anderson faced off against Zoie Shreiweis at age 23. She was coming in with a record of 0-1 (0). Anderson lost the fight via 3-round majority decision.