Lauren Murphy has seven losses against seven opponents on her MMA record. For a list of Murphy's best fights, refer to "Best fights of Lauren Murphy".
On July 12, 2025 Lauren Murphy faced off against Eduarda Moura in a flyweight bout at age 41. She was coming in with a record of 16-7 (9). Murphy lost the fight via 3-round unanimous decision.
On January 21, 2023 Lauren Murphy faced off against Jéssica Andrade in a flyweight bout at age 39. She was coming in with a record of 16-6 (9), and Andrade was 31 years old and with a record of 23-9 (17). Murphy lost the fight via 3-round unanimous decision.
On September 25, 2021 Lauren Murphy fought Valentina Shevchenko in a flyweight title fight for Shevchenko's UFC Women's Championship title. Murphy was 38 years old and with a record of 15-5 (9), and Shevchenko was 33 years old and with a record of 21-3 (14). Murphy lost the fight via 4th-round TKO.
On June 1, 2018 Lauren Murphy faced off against Sijara Eubanks in a flyweight bout at age 34. She was coming in with a record of 10-4 (7), and Eubanks was 33 years old and with a record of 2-2 (2). Murphy lost the fight via 3-round unanimous decision.
On July 13, 2016 Lauren Murphy faced off against Katlyn Chookagian in a bantamweight bout at age 32. She was coming in with a record of 9-3 (7). Murphy lost the fight via 3-round unanimous decision.
On April 4, 2015 Lauren Murphy faced off against Liz Carmouche in a bantamweight bout at age 31. She was coming in with a record of 8-2 (6), and Carmouche was 31 years old and with a record of 9-5 (8). Murphy lost the fight via 3-round unanimous decision.
On August 16, 2014 Lauren Murphy faced off against Sara McMann in a bantamweight bout at age 31. She was coming in with a record of 8-1 (6), and McMann was 33 years old and with a record of 7-1 (4). Murphy lost the fight via 3-round split decision.