Justin Gaethje has five losses against five opponents on his MMA record. For a list of Gaethje's best fights, refer to "Best fights of Justin Gaethje".
On April 13, 2024 Justin Gaethje faced off against Max Holloway in a lightweight bout at age 35. He was coming in with a record of 25-5 (21), and Holloway was 32 years old and with a record of 25-7 (13). Gaethje lost the fight via 5th-round KO.
On May 7, 2022 Justin Gaethje fought Charles Oliveira in a lightweight title fight for the UFC Championship title. Gaethje was 33 years old and with a record of 23-4 (20), and Oliveira was 32 years old and with a record of 32-8 (29). Gaethje lost the fight via 1st-round submission.
On October 24, 2020 Justin Gaethje fought Khabib Nurmagomedov in a lightweight title fight for Nurmagomedov's UFC Championship title. Gaethje was 31 years old and with a record of 22-3 (20), and Nurmagomedov was 32 years old and with a record of 28-0 (18). Gaethje lost the fight via 2nd-round choke-out.
On April 14, 2018 Justin Gaethje faced off against Dustin Poirier in a lightweight bout at age 29. He was coming in with a record of 18-2 (16), and Poirier was 29 years old and with a record of 22-5 (17). Gaethje lost the fight via 4th-round TKO.
On December 2, 2017 Justin Gaethje faced off against Eddie Alvarez in a lightweight bout at age 29. He was coming in with a record of 18-1 (16), and Alvarez was 33 years old and with a record of 28-5 (21). Gaethje lost the fight via 3rd-round KO.