Juan Espino has two losses against two opponents on his MMA record. For a list of Espino's best fights, refer to "Best fights of Juan Espino".
On April 17, 2021 Juan Espino faced off against Alexander Romanov in a heavyweight bout at age 40. He was coming in with a record of 10-2 (8), and Romanov was 30 years old and with a record of 13-0 (12). Espino lost the fight via 3-round split decision.
On April 21, 2011 Juan Espino faced off against Vitaly Minakov at age 30. He was coming in with a record of 2-1 (2), and Minakov was 26 years old and with a record of 4-0 (3). Espino lost the fight via 1st-round TKO.