Don Frye has nine losses against eight opponents on his MMA record. For a list of Frye's best fights, refer to "Best fights of Don Frye".
On December 11, 2011 Don Frye faced off against Ruben Villareal at age 46. He was coming in with a record of 20-9-1 (18). Frye lost the fight via 1st-round KO.
On September 12, 2009 Don Frye faced off against Dave Herman at age 43. He was coming in with a record of 20-8-1 (18), and Herman was 24 years old and with a record of 16-1 (16). Frye lost the fight via 1st-round TKO.
On August 16, 2008 Don Frye faced off against Ikuhisa Minowa at age 42. He was coming in with a record of 19-7-1 (17), and Minowa was 32 years old and with a record of 39-28-8 (31). Frye lost the fight via 1st-round submission.
On April 8, 2007 Don Frye faced off against James Thompson at age 41. He was coming in with a record of 18-6-1 (16), and Thompson was 28 years old and with a record of 13-6 (12). Frye lost the fight via 1st-round TKO.
On December 31, 2004 Don Frye faced off against Yoshihiro Nakao at age 39. He was coming in with a record of 15-5 (13), and Nakao was 32 years old and with a record of 2-0 (1). Frye lost the fight via 3-round unanimous decision.
On December 31, 2003 Don Frye faced off against Gary Goodridge at age 38. He was coming in with a record of 15-4 (13), and Goodridge was 37 years old and with a record of 18-14-1 (17). Frye lost the fight via 1st-round KO.
On June 8, 2003 Don Frye faced off against Mark Coleman at age 37. He was coming in with a record of 15-3 (13), and Coleman was 38 years old and with a record of 12-5 (10). Frye lost the fight via 3-round unanimous decision.
On November 24, 2002 Don Frye faced off against Hidehiko Yoshida at age 37. He was coming in with a record of 15-2 (13), and Yoshida was 33 years old and with a record of . Frye lost the fight via 1st-round choke-out.
On July 12, 1996 Don Frye fought Mark Coleman in a null title fight for Coleman's UFC 10 Tournament Championship title. Frye was 30 years old and with a record of 6-1 (6), and Coleman was 31 years old and with a record of 2-0 (2). Frye lost the fight via 1st-round TKO.