Dominick Reyes has four losses against four opponents on his MMA record. For a list of Reyes's best fights, refer to "Best fights of Dominick Reyes".
On November 12, 2022 Dominick Reyes faced off against Ryan Spann in a light-heavyweight bout at age 32. He was coming in with a record of 12-4 (9), and Spann was 31 years old and with a record of 20-7 (17). Reyes lost the fight via 1st-round KO.
On May 1, 2021 Dominick Reyes faced off against Jiří Procházka in a light-heavyweight bout at age 31. He was coming in with a record of 12-3 (9), and Procházka was 28 years old and with a record of 27-3-1 (26). Reyes lost the fight via 2nd-round KO.
On September 27, 2020 Dominick Reyes fought Jan Błachowicz in a light-heavyweight title fight for the UFC Championship title. Reyes was 30 years old and with a record of 12-2 (9), and Błachowicz was 37 years old and with a record of 26-8 (16). Reyes lost the fight via 2nd-round TKO.
On February 8, 2020 Dominick Reyes fought Jon Jones in a light-heavyweight title fight for Jones' UFC Championship title. Reyes was 30 years old and with a record of 12-1 (9), and Jones was 32 years old and with a record of 25-1 (15). Reyes lost the fight via 5-round unanimous decision.
