Derek Anderson has four losses against four opponents on his MMA record. For a list of Anderson's best fights, refer to "Best fights of Derek Anderson".
On May 7, 2021 Derek Anderson faced off against Michael Page in a welterweight bout at age 31. He was coming in with a record of 17-4 (12), and Page was 34 years old and with a record of 18-1 (14). Anderson lost the fight via 1st-round TKO.
On January 21, 2017 Derek Anderson faced off against Derek Campos in a lightweight bout at age 26. He was coming in with a record of 14-3 (11), and Campos was 28 years old and with a record of 17-6 (10). Anderson lost the fight via 3-round unanimous decision.
On August 28, 2015 Derek Anderson faced off against Brent Primus in a lightweight bout at age 25. He was coming in with a record of 12-2 (11), and Primus was 30 years old and with a record of 5-0 (5). Anderson lost the fight via 3-round split decision.
On April 18, 2014 Derek Anderson faced off against Marcin Held in a lightweight bout at age 24. He was coming in with a record of 11-1 (10), and Held was 22 years old and with a record of 17-3 (13). Anderson lost the fight via 2nd-round submission.