Demetrious Johnson has four losses against four opponents on his MMA record. For a list of Johnson's best fights, refer to "Best fights of Demetrious Johnson".
On April 7, 2021 Demetrious Johnson fought Adriano Moraes in a flyweight title fight for Moraes' ONE Championship title. Johnson was 34 years old and with a record of 23-4-1 (12), and Moraes was 32 years old and with a record of 18-3 (12). Johnson lost the fight via 2nd-round KO.
On August 4, 2018 Demetrious Johnson met Henry Cejudo in a flyweight (UFC Championship) title defense fight. Johnson was 31 years old and with a record of 20-3-1 (11), and Cejudo was 31 years old and with a record of 12-2 (5). Johnson lost the fight via 5-round split decision and lost the title.
On October 1, 2011 Demetrious Johnson fought Dominick Cruz in a bantamweight title fight for Cruz' UFC Championship title. Johnson was 25 years old and with a record of 7-2 (4), and Cruz was 26 years old and with a record of 18-1 (7). Johnson lost the fight via 5-round unanimous decision.
On April 24, 2010 Demetrious Johnson faced off against Brad Pickett at age 23. He was coming in with a record of 3-1 (3), and Pickett was 31 years old and with a record of 18-4 (15). Johnson lost the fight via 3-round unanimous decision.