Darren Uyenoyama has six losses against six opponents on his MMA record. For a list of Uyenoyama's best fights, refer to "Best fights of Darren Uyenoyama".
On November 18, 2016 Darren Uyenoyama faced off against Riley Dutro in a flyweight bout at age 37. He was coming in with a record of 10-6 (6). Uyenoyama lost the fight via 1st-round TKO.
On December 14, 2013 Darren Uyenoyama faced off against Alp Ozkilic in a flyweight bout at age 34. He was coming in with a record of 8-5 (5), and Ozkilic was 27 years old and with a record of 8-1 (3). Uyenoyama lost the fight via 3-round split decision.
On April 20, 2013 Darren Uyenoyama faced off against Joseph Benavidez in a flyweight bout at age 33. He was coming in with a record of 8-4 (5), and Benavidez was 28 years old and with a record of 17-3 (12). Uyenoyama lost the fight via 2nd-round TKO.
On April 17, 2010 Darren Uyenoyama faced off against Tomoya Miyashita at age 30. He was coming in with a record of 5-3 (3). Uyenoyama lost the fight via 2nd-round submission.
On June 15, 2008 Darren Uyenoyama faced off against Hideo Tokoro at age 28. He was coming in with a record of 4-2 (3), and Tokoro was 30 years old and with a record of 22-17-2 (18). Uyenoyama lost the fight via 2-round unanimous decision.
On October 6, 2007 Darren Uyenoyama faced off against Rolando Velasco at age 27. He was coming in with a record of 2-1 (1). Uyenoyama lost the fight via 3-round unanimous decision.