Ciryl Gane has two losses against two opponents on his MMA record. For a list of Gane's best fights, refer to "Best fights of Ciryl Gane".
On March 4, 2023 Ciryl Gane fought Jon Jones in a heavyweight title fight for the UFC Championship title. Gane was 32 years old and with a record of 11-2 (8), and Jones was 35 years old and with a record of 26-1 (15). Gane lost the fight via 1st-round submission.
On January 22, 2022 Ciryl Gane fought Francis Ngannou in a heavyweight title fight for Ngannou's UFC Championship title. Gane was 31 years old and with a record of 10-1 (7), and Ngannou was 35 years old and with a record of 16-3 (16). Gane lost the fight via 5-round unanimous decision.