Charmaine Tweet has six losses against six opponents on her MMA record. For a list of Tweet's best fights, refer to "Best fights of Charmaine Tweet".
On January 14, 2017 Charmaine Tweet fought Megan Anderson in a featherweight title fight for Anderson's Invicta FC Championship title. Tweet was 39 years old and with a record of 9-6 (8), and Anderson was 26 years old and with a record of 7-2 (5). Tweet lost the fight via 2nd-round TKO.
On February 27, 2015 Charmaine Tweet fought Cris Cyborg in a featherweight title fight for Cyborg's Invicta FC Championship title. Tweet was 37 years old and with a record of 6-5 (6), and Cyborg was 29 years old and with a record of 12-1 (10). Tweet lost the fight via 1st-round TKO.
On December 7, 2013 Charmaine Tweet faced off against Julia Budd at age 36. She was coming in with a record of 4-4 (4), and Budd was 30 years old and with a record of 5-2 (4). Tweet lost the fight via 3-round unanimous decision.
On June 15, 2012 Charmaine Tweet faced off against Adrienne Seiber at age 35. She was coming in with a record of 1-3 (1). Tweet lost the fight via 3-round split decision.
On October 1, 2011 Charmaine Tweet faced off against Anna Barone at age 34. She was coming in with a record of 0-2 (0). Tweet lost the fight via 1st-round KO.
On June 17, 2011 Charmaine Tweet faced off against Ronda Rousey at age 34. She was coming in with a record of 0-1 (0), and Rousey was 24 years old and with a record of 1-0 (1). Tweet lost the fight via 1st-round submission.