Bruno Santos has five losses against five opponents on his MMA record. For a list of Santos's best fights, refer to "Best fights of Bruno Santos".
On June 9, 2023 Bruno Santos faced off against Jared Revel in a middleweight bout at age 35. He was coming in with a record of 19-5-1 (2). Santos lost the fight via 2nd-round choke-out.
On February 21, 2020 Bruno Santos faced off against Artem Frolov in a middleweight bout at age 32. He was coming in with a record of 18-4-1 (2). Santos lost the fight via 2nd-round KO.
On August 31, 2019 Bruno Santos faced off against Vyacheslav Babkin in a middleweight bout at age 32. He was coming in with a record of 18-3-1 (2). Santos lost the fight via 1st-round TKO.
On October 4, 2014 Bruno Santos faced off against Elias Theodorou in a middleweight bout at age 27. He was coming in with a record of 14-2 (2), and Theodorou was 26 years old and with a record of 9-0 (6). Santos lost the fight via 3-round unanimous decision.
On December 7, 2013 Bruno Santos faced off against Krzysztof Jotko in a middleweight bout at age 26. He was coming in with a record of 13-1 (2), and Jotko was 24 years old and with a record of 13-0 (6). Santos lost the fight via 3-round unanimous decision.