Alex Karalexis has six losses against six opponents on his MMA record. For a list of Karalexis's best fights, refer to "Best fights of Alex Karalexis".
On June 10, 2011 Alex Karalexis faced off against Tiawan Howard at age 33. He was coming in with a record of 10-6 (6). Karalexis lost the fight via 3-round split decision.
On April 24, 2010 Alex Karalexis faced off against Anthony Pettis at age 32. He was coming in with a record of 10-5 (6), and Pettis was 23 years old and with a record of 10-1 (9). Karalexis lost the fight via 2nd-round submission.
On December 3, 2008 Alex Karalexis faced off against Bart Palaszewski at age 31. He was coming in with a record of 9-4 (5), and Palaszewski was 25 years old and with a record of 30-11 (23). Karalexis lost the fight via 2nd-round TKO.
On December 12, 2007 Alex Karalexis faced off against Ed Ratcliff at age 30. He was coming in with a record of 9-3 (5), and Ratcliff was 24 years old and with a record of 5-0 (5). Karalexis lost the fight via 2nd-round TKO.
On January 16, 2006 Alex Karalexis faced off against Jason Von Flue at age 28. He was coming in with a record of 5-2 (3), and Von Flue was 30 years old and with a record of 10-4-1 (9). Karalexis lost the fight via 3rd-round choke-out.
On August 6, 2005 Alex Karalexis faced off against Kenny Florian at age 27. He was coming in with a record of 5-1 (3), and Florian was 29 years old and with a record of 2-2 (2). Karalexis lost the fight via 2nd-round TKO.