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Shane Mosley had a total of 10 losses in his professional boxing career — seven of them in title bouts and three in non-title bouts. He suffered his first loss against Vernon Forrest via 12 round unanimous decision on January 26, 2002, which ended his 38-fight win streak. He has been stopped once and lost nine times via decision.
David Avanesyan, Anthony Mundine, Canelo Álvarez, Manny Pacquiao, and Floyd Mayweather Jr. are some of the boxers who have beaten Mosley.
This is the first loss in Shane Mosley's career. Mosley lost to Vernon Forrest via 12 round unanimous decision on . He was defending his welterweight WBC title, and fighting for the vacant The Ring title. He was 30 years old with a record of 38-0. Forrest was also 30 years old, with a record of 33-0.
On Mosley lost to Vernon Forrest in the rematch via 12 round unanimous decision. He was fighting for Forrest's welterweight WBC and The Ring titles, he was 30 years old with a record of 38-1. Forrest was 31 years old with a record of 34-0.
On Mosley lost to Winky Wright via 12 round unanimous decision. He was defending his super-welterweight WBA (Super), WBC, and The Ring titles, and fighting for Wright's super-welterweight IBF title, he was 32 years old with a record of 39-2. Wright was also 32 years old, with a record of 46-3.
On Mosley lost to Winky Wright in the rematch via 12 round majority decision. He was fighting for Wright's super-welterweight WBA (Super), WBC, and The Ring titles, he was 33 years old with a record of 39-3. Wright was 32 years old with a record of 47-3.
On Mosley lost to Puerto Rican boxer Miguel Cotto via 12 round unanimous decision. He was fighting for Cotto's welterweight WBA title, he was 36 years old with a record of 44-4. Cotto was 27 years old with a record of 30-0.
On Mosley lost to Floyd Mayweather Jr. via 12 round unanimous decision in a non-title bout. He was 38 years old with a record of 46-5. Mayweather Jr. was 33 years old with a record of 40-0.
On Mosley lost to Filipino boxer Manny Pacquiao via 12 round unanimous decision. He was fighting for Pacquiao's welterweight WBO title, he was 39 years old with a record of 46-6-1. Pacquiao was 32 years old with a record of 52-3-2.
On Mosley lost to Mexican boxer Canelo Álvarez via 12 round unanimous decision. He was fighting for Álvarez' super-welterweight WBC title, he was 40 years old with a record of 46-7-1. Canelo was 21 years old with a record of 39-0-1.
On Mosley lost to Australian boxer Anthony Mundine via 7th round RTD in a non-title bout. He was 42 years old with a record of 47-8-1. Mundine was 38 years old with a record of 44-5.
On Mosley lost to Russian boxer David Avanesyan via 12 round unanimous decision in a non-title bout. He was 44 years old with a record of 49-9-1. Avanesyan was 27 years old with a record of 21-1-1.