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Ruben Castillo had 79 fights with 35 KO wins. Some of his best fights among these have been against Alexis Arguello, Salvador Sanchez, Juan Laporte, Kelvin Lampkin, and Hector Carrasquilla. The following are Castillo's top 10 fights.
On Ruben Castillo lost to Nicaraguan boxer Alexis Arguello via 11th round TKO. Castillo was 22 years old with a record of 43-1 (21 KOs). Argüello was 27 years old with a record of 60-5 (50 KOs). Despite the loss, Castillo put on a good fight till it lasted. The performance in this fight is the number one among all of Castillo's fights.
On Ruben Castillo lost to Mexican boxer Salvador Sanchez via 15 round unanimous decision. Castillo was 22 years old with a record of 44-2 (22 KOs). Sánchez was 21 years old with a record of 34-1-1 (28 KOs). Despite the loss, Castillo put on a good fight. This fight is the second best performance in Castillo's career.
On Ruben Castillo lost to Puerto Rican boxer Juan Laporte via 12 round unanimous decision. Castillo was 25 years old with a record of 54-4-2 (28 KOs). Laporte was 23 years old with a record of 22-3 (13 KOs). Despite the loss, Castillo put on a good fight.
On Ruben Castillo defeated Kelvin Lampkin in the rematch via 2nd round TKO. Castillo was 23 years old with a record of 48-3-1 (24 KOs).
On Ruben Castillo defeated Hector Carrasquilla via 3rd round TKO. Castillo was 21 years old with a record of 39-0 (18 KOs).
On Ruben Castillo defeated Roberto Torres via 3rd round KO. Castillo was 21 years old with a record of 40-0 (19 KOs).
On Ruben Castillo defeated Fred Rolando Pastor via 4th round KO. Castillo was 21 years old with a record of 42-0 (20 KOs).
On Ruben Castillo defeated Antonio Becerra via 3rd round KO. Castillo was 23 years old with a record of 49-3-1 (25 KOs).
On Ruben Castillo defeated Juan Escobar via 8th round KO. Castillo was 21 years old with a record of 43-0 (21 KOs).
On Ruben Castillo defeated Roberto Quintanilla via 2nd round KO. Castillo was 21 years old with a record of 36-0 (17 KOs).