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Manuel Medina had a total of 16 losses in his professional boxing career — 11 of them in title bouts and five in non-title bouts. He suffered his first loss against Gerardo Martinez via 4 round PTS on December 5, 1985. He has been stopped eight times and lost eight times via decision.
Malcolm Klassen, Cassius Baloyi, Scott Harrison, Juan Manuel Márquez, and Johnny Tapia are some of the boxers who have beaten Medina.
This is the first loss in Manuel Medina's career. Medina lost to Gerardo Martinez via 4 round PTS on in a non-title bout. He was 14 years old with a record of 2-0.
On Medina lost to Alex Madrid via 4th round TKO in a non-title bout. He was 14 years old with a record of 2-1.
On Medina lost to Juan Carlos Salazar via 10th round TKO in a non-title bout. He was 18 years old with a record of 29-2.
On Medina lost to Tom Johnson in a rematch via 12 round split decision. He was defending his featherweight IBF title, he was 21 years old with a record of 46-3.
On Medina lost to Puerto Rican boxer John John Molina via 12 round unanimous decision. He was fighting for Molina's super-featherweight IBF title, he was 22 years old with a record of 47-4. Molina was 28 years old with a record of 31-3.
On Medina lost to Tom Johnson in a rematch via 12 round unanimous decision. He was fighting for Johnson's featherweight IBF title, he was 23 years old with a record of 49-5.
On Medina lost to Filipino boxer Luisito Espinosa via 12 round unanimous decision. He was defending his featherweight WBC title, he was 24 years old with a record of 51-6. Espinosa was 28 years old with a record of 36-7.
On Medina lost to British boxer Naseem Hamed via 11th round TKO. He was fighting for Hamed's featherweight WBO title, he was 25 years old with a record of 52-7. Hamed was 22 years old with a record of 22-0.
On Medina lost to Filipino boxer Luisito Espinosa in a rematch via 8 round technical decision. He was fighting for Espinosa's featherweight WBC title, he was 26 years old with a record of 53-8. Espinosa was 29 years old with a record of 40-7.
On Medina lost to Derrick Gainer via 9th round KO in a non-title bout. He was 26 years old with a record of 53-9.
On Medina lost to British boxer Paul Ingle via 12 round unanimous decision. He was defending his featherweight IBF title, he was 28 years old with a record of 56-10. Ingle was 27 years old with a record of 21-1.
On Medina lost to American boxer Johnny Tapia via 12 round majority decision. He was defending his featherweight IBF title, he was 31 years old with a record of 60-11. Tapia was 35 years old with a record of 51-2-2.
On Medina lost to fellow Mexican boxer Juan Manuel Márquez via 7th round TKO. He and Márquez were fighting for the vacant featherweight IBF title. He was 31 years old with a record of 60-12. Márquez was 29 years old with a record of 39-2.
On Medina lost to Scott Harrison in the rematch via 11th round TKO. He was defending his featherweight WBO title, he was 32 years old with a record of 63-13.
On Medina lost to Cassius Baloyi via 11th round TKO. He and Baloyi were fighting for the vacant super-featherweight IBF title. He was 35 years old with a record of 66-14.
On Medina lost to Malcolm Klassen via 2nd round TKO in a non-title bout. He was 37 years old with a record of 67-15-1.