Wilfredo Méndez has two losses against two opponents on his boxing record. For a list of Méndez's best fights, refer to "Best fights of Wilfredo Méndez".
On December 14, 2021 Wilfredo Méndez met Masataka Taniguchi in a strawweight (WBO) world-title defense fight. Méndez was 25 years old and with a record of 16-2 (6), and Taniguchi was 27 years old and with a record of 14-3 (9). Méndez lost the fight via 11th-round TKO and lost the title.
On March 17, 2018 Wilfredo Méndez faced off against Leyman Benavides in a strawweight bout at age 21. He was coming in with a record of 9-1 (4). Méndez lost the fight via 11-round unanimous decision.
