José Uzcátegui has five losses against five opponents on his boxing record. For a list of Uzcátegui's best fights, refer to "Best fights of José Uzcátegui".
On December 17, 2022 José Uzcátegui faced off against Vladimir Shishkin in a super-middleweight bout at age 31. He was coming in with a record of 32-5 (27), and Shishkin was 31 years old and with a record of 13-0 (8). Uzcátegui lost the fight via 12-round unanimous decision.
On December 28, 2019 José Uzcátegui faced off against Lionell Thompson in a super-middleweight bout at age 29. He was coming in with a record of 29-4 (24). Uzcátegui lost the fight via 10-round unanimous decision.
On January 13, 2019 José Uzcátegui met Caleb Plant in a super-middleweight (IBF) world-title defense fight. Uzcátegui was 28 years old and with a record of 28-3 (23), and Plant was 26 years old and with a record of 17-0 (10). Uzcátegui lost the fight via 12-round unanimous decision and lost the title.
On May 20, 2017 José Uzcátegui fought Andre Dirrell in a super-middleweight world-title fight for the IBF title. Uzcátegui was 26 years old and with a record of 26-2 (22), and Dirrell was 33 years old and with a record of 25-2 (16). Uzcátegui lost the fight via 8-round disqualification.
On June 28, 2014 José Uzcátegui faced off against Matt Korobov in a middleweight bout at age 23. He was coming in with a record of 22-1 (18), and Korobov was 31 years old and with a record of 23-0 (14). Uzcátegui lost the fight via 10-round unanimous decision.
