Here is a list of Uzcátegui's best fights. For a list of Uzcátegui's losses, refer to "José Uzcátegui Losses".
On February 16, 2013 José Uzcátegui faced off against Rogelio Medina at age 22. He was coming in with a record of 17-0 (13), and Medina was 24 years old and with a record of 30-2 (24). Uzcátegui won the fight via 10-round unanimous decision.
On March 3, 2018 José Uzcátegui fought Andre Dirrell in a super-middleweight world-title fight for Dirrell's IBF title. Uzcátegui was 27 years old and with a record of 27-2 (23), and Dirrell was 34 years old and with a record of 26-2 (16). Uzcátegui stopped Andre Dirrell via 8th-round retirement and is crowned the new super-middleweight world champion.
On September 28, 2018 José Uzcátegui faced off against Ezequiel Osvaldo Maderna in a super-middleweight bout at age 27. He was coming in with a record of 28-2 (23), and Maderna was 31 years old and with a record of 26-4 (16). Uzcátegui won the fight via 10-round unanimous decision.
On March 26, 2021 José Uzcátegui faced off against Josue Obando in a super-middleweight bout at age 30. He was coming in with a record of 30-4 (25), and Obando was 31 years old and with a record of 20-28-2 (15). Uzcátegui stopped Josue Obando via TKO.