Here is a list of Chamberlain's best fights. For a list of Chamberlain's losses, refer to "Isaac Chamberlain Losses".
On October 21, 2023 Isaac Chamberlain faced off against Mikael Lawal in a cruiserweight bout at age 29. He was coming in with a record of 16-2 (8), and Lawal was 28 years old and with a record of 17-0 (11). Chamberlain won the fight via 12-round unanimous decision.
On December 12, 2021 Isaac Chamberlain faced off against Dilan Prašović in a cruiserweight bout at age 27. He was coming in with a record of 14-1 (8). Chamberlain stopped Dilan Prašović via KO.
