Drian Francisco has six losses against six opponents on his boxing record. For a list of Francisco's best fights, refer to "Best fights of Drian Francisco".
On May 26, 2018 Drian Francisco faced off against Eduardo Hernández in a super-bantamweight bout at age 35. He was coming in with a record of 29-6-1 (22), and Hernández was 20 years old and with a record of 24-0 (21). Francisco lost the fight via 2nd-round retirement.
On January 27, 2018 Drian Francisco faced off against Edivaldo Ortega in a super-bantamweight bout at age 35. He was coming in with a record of 29-5-1 (22). Francisco lost the fight via 10-round unanimous decision.
On November 21, 2015 Drian Francisco faced off against Guillermo Rigondeaux in a super-bantamweight bout at age 33. He was coming in with a record of 28-4-1 (22), and Rigondeaux was 35 years old and with a record of 15-0 (10). Francisco lost the fight via 10-round unanimous decision.
On May 30, 2015 Drian Francisco faced off against Jason Canoy Manigos in a super-bantamweight bout at age 32. He was coming in with a record of 27-3-1 (21). Francisco lost the fight via 1st-round TKO.
On July 12, 2013 Drian Francisco faced off against Chris Avalos in a super-bantamweight bout at age 30. He was coming in with a record of 24-2-1 (19). Francisco lost the fight via 10-round unanimous decision.
On May 1, 2011 Drian Francisco faced off against Tepparith Singwancha in a super-flyweight bout at age 28. He was coming in with a record of 20-1-1 (16). Francisco lost the fight via 12-round unanimous decision.