Here is a list of Francisco's best fights. For a list of Francisco's losses, refer to "Drian Francisco Losses".
On October 3, 2009 Drian Francisco faced off against Roberto Vásquez in a flyweight bout at age 26. He was coming in with a record of 18-0-1 (14), and Vásquez was 25 years old and with a record of 27-3 (20). Francisco stopped Roberto Vásquez via TKO.