William Scull has one loss against one opponent on his boxing record. For a list of Scull's best fights, refer to "Best fights of William Scull".
On May 3, 2025 William Scull, the IBF champion, met Canelo Álvarez, the WBA (Super), WBC, WBO and The Ring champion, in a super-middleweight world-title unification fight. Scull was 32 years old and with a record of 23-1 (9), and Álvarez was 34 years old and with a record of 62-2-2 (39). Scull lost the fight via 12-round unanimous decision and lost his title.