Juan Manuel López has six losses against five opponents on his boxing record. For a list of López's best fights, refer to "Best fights of Juan Manuel López".
On March 3, 2018 Juan Manuel López faced off against Jayson Vélez at age 34. He was coming in with a record of 35-6 (32), and Vélez was 29 years old and with a record of 3-4-1 (1). López lost the fight via 12th-round TKO.
On September 11, 2014 Juan Manuel López fought Jesús Cuellar in a featherweight world-title fight for Cuellar's WBA title. López was 31 years old and with a record of 34-5 (31), and Cuellar was 27 years old and with a record of 24-1 (18). López lost the fight via 2nd-round KO.
On July 12, 2014 Juan Manuel López faced off against Francisco Vargas in a super-featherweight bout at age 31. He was coming in with a record of 34-4 (31), and Vargas was 29 years old and with a record of 19-0-1 (13). López lost the fight via 3rd-round retirement.
On June 15, 2013 Juan Manuel López fought Mikey Garcia in a featherweight world-title fight for the The Ring and WBO titles. López was 29 years old and with a record of 33-3 (30), and Garcia was 25 years old and with a record of 31-0 (26). López lost the fight via 4th-round TKO.
On March 10, 2012 Juan Manuel López fought Orlando Salido in a featherweight world-title fight for Salido's WBO title. López was 28 years old and with a record of 31-2 (28), and Salido was 31 years old and with a record of 38-11-2 (26). López lost the fight via 10th-round TKO.
On April 16, 2011 Juan Manuel López met Orlando Salido in a featherweight (WBO) world-title defense fight. López was 27 years old and with a record of 30-1 (27), and Salido was 30 years old and with a record of 35-11-2 (23). López lost the fight via 8th-round TKO and lost the title.
