Jermell Charlo has two losses against two opponents on his boxing record. For a list of Charlo's best fights, refer to "Best fights of Jermell Charlo".
On September 30, 2023 Jermell Charlo fought Canelo Álvarez in a super-middleweight world-title fight for Álvarez' WBA (Super), WBC, IBF, WBO and The Ring titles. Charlo was 33 years old and with a record of 35-2-1 (19), and Álvarez was 33 years old and with a record of 59-2-2 (39). Charlo lost the fight via 12-round unanimous decision.
On December 22, 2018 Jermell Charlo met Tony Harrison in a super-welterweight (WBC) world-title defense fight. Charlo was 28 years old and with a record of 31-1 (15), and Harrison was 28 years old and with a record of 27-2 (21). Charlo lost the fight via 12-round unanimous decision and lost the title.