Jeison Rosario has five losses against five opponents on his boxing record. For a list of Rosario's best fights, refer to "Best fights of Jeison Rosario".
On February 1, 2025 Jeison Rosario faced off against Jesus Ramos Jr. in a super-welterweight bout at age 29. He was coming in with a record of 24-5-2 (18), and Ramos Jr. was 23 years old and with a record of 21-1 (17). Rosario lost the fight via 8th-round TKO.
On November 5, 2022 Jeison Rosario faced off against Brian Mendoza at age 27. He was coming in with a record of 23-4-1 (17), and Mendoza was 28 years old and with a record of 20-2 (14). Rosario lost the fight via 5th-round KO.
On June 26, 2021 Jeison Rosario faced off against Erickson Lubin in a super-welterweight bout at age 26. He was coming in with a record of 20-3-1 (14), and Lubin was 25 years old and with a record of 23-1 (16). Rosario lost the fight via 6th-round KO.
On September 26, 2020 Jeison Rosario, the WBA (Super) and IBF champion, met Jermell Charlo, the WBC and The Ring champion, in a super-welterweight world-title unification fight. Rosario was 25 years old and with a record of 20-2-1 (14), and Charlo was 30 years old and with a record of 33-1 (17). Rosario lost the fight via 8th-round KO and lost his titles.
On April 29, 2017 Jeison Rosario faced off against Nathaniel Gallimore at age 22. He was coming in with a record of 12-1 (9), and Gallimore was 28 years old and with a record of 17-1-1 (14). Rosario lost the fight via 6th-round TKO.